Pemphigus Vegetans (PVeg) is a rare variant of pemphigus vulgaris, an autoimmune blistering disorder typically affecting adults. It is characterized by hypertrophic vegetating lesions and flaccid pustules, often preceded by lesions in the oral cavity.
Increased Bleeding Volume during Tympanoplasty (BDT), in addition to disturbing the surgeon's vision, increases the need for transfusion of blood products and the risk of a hemolytic reaction. This study aimed to compare the effect of intravenous infusion of Dexmedetomidine (D) and Magnesium Sulfate (MS) on BDT.
Recent advances in cystic fibrosis therapeutics have resulted in the development of CFTR modulators that have led to great improvements in CF care. Novel adverse effects are still being reported. A case of brittle nails that were reported after initiation of treatment with Elexacaftor/Tezacaftor/Ivacaftor (ETI) is presented here. The parents have provided informed consent for this case presentation.
A restrained 17-year-old male initially presented to the emergency department following a high-speed motor vehicle collision with no active complaints. Exam was reassuring notable only for a knee abrasion and patient was discharged home. The following day patient had some vague abdominal plate and the primary physician ordered an abdominal flat plate was obtained at that time (Figure 1).
Acute Subdural Hematoma (ASDH) in an infant without external signs of head trauma is sometimes thought to be symptomatic of Shaken Baby Syndrome (SBS) or Abusive Head Trauma (AHT) in the United States or of Infantile Acute Subdural Hematoma (IASDH) due to minor head trauma in Japan
Primary heart cancers are rare, but cancer metastases occur much more often, which is why they are diagnosed mainly in non-oncology departments. Approximately 85% of heart cancers are benign, with myxoma predominating [1,4].
Ventriculoperitoneal Shunt (VPS) infection is a significant and relatively common complication in pediatric patients. Current guidelines recommend empirical treatment with vancomycin and an antipseudomonal beta-lactam antibiotic, followed by surgical removal of the infected VPS. However, adding rifampicin, known for its antibiofilm activity, may allow for successful treatment without the need for shunt removal.
Rhinitis Medicamentosa (RM), commonly known as rebound nasal congestion, is an increasingly prevalent condition among young individuals who chronically use topical nasal decongestants. This article explores the development of RM, highlighting the mechanisms, clinical features, prevalence, risk factors, and management strategies.
Chronic disseminated candidiasis is a clinical condition severely affecting patients with hematological malignancies. It has been mainly reported in adult patients, while cases in children and adolescents are rare. Diagnosis is challenging and not well established yet, but a thorough clinical examination can be helpful.
Osteogenesis Imperfecta (OI) is a genetic disorder primarily resulting from pathogenic variants in the COL1A1 or COL1A2 genes, responsible for collagen synthesis. This autosomal dominant condition is characterized by high morbidity and mortality due to its disabling symptoms, including pain and skeletal deformities. OI is a rare disease and part of the group of orphan diseases.